Zebrafish behavioral profiling identifies multitarget antipsychotic-like compounds. Bruni G, Rennekamp AJ, Velenich A, McCarroll M, Gendelev L, Fertsch E, Taylor J, Lakhani P, Lensen D, Evron T, Lorello PJ, Huang XP, Kolczewski S, Carey G, Caldarone BJ, Prinssen E, Roth BL, Keiser MJ, Peterson RT, Kokel D. Nat Chem Biol. 2016
- σ1 receptor ligands control a switch between passive and active threat responses. Rennekamp AJ, Huang XP, Wang Y, Patel S, Lorello PJ, Cade L, Gonzales AP, Yeh JR, Caldarone BJ, Roth BL, Kokel D, Peterson RT. Nat Chem Biol. 2016
- Leveraging Large-scale Behavioral Profiling in Zebrafish to Explore Neuroactive Polypharmacology. McCarroll MN, Gendelev L, Keiser MJ, Kokel D. ACS Chem Biol. 2016
Discovering novel neuroactive drugs through high-throughput behavior-based chemical screening in the zebrafish. Bruni G, Lakhani P, Kokel D. Front Pharmacol. 2014
- Photochemical control of TRPA1 channels in neurons and animals. Kokel D, Cheung CY, Mills R, Coutinho-Budd J, Huang L, Setola V, Sprague J, Jin S, Jin YN, Huang XP, Bruni G, Woolf CJ, Roth BL, Hamblin MR, Zylka MJ, Milan DJ, Peterson RT. Nat Chem Biol. 2013
Identification of Nonvisual Photomotor Response Cells in the Vertebrate Hindbrain. Kokel D, Dunn TW, Ahrens MB, Alshut R, Cheung CY, Saint-Amant L, Bruni G, Mateus R, van Ham TJ, Shiraki T, Fukada Y, Kojima D, Yeh JR, Mikut R, von Lintig J, Engert F, Peterson RT. J Neurosci. 2013
- Behavioral barcoding in the cloud: embracing data-intensive digital phenotyping in neuropharmacology. Kokel D, Rennekamp AJ, Shah AH, Liebel U, Peterson RT. Trends Biotechnol. 2012
- Chemical informatics and target identification in a zebrafish phenotypic screen. Laggner C, Kokel D**, Setola V, Tolia A, Lin H, Irwin JJ, Keiser MJ, Cheung CY, Minor DL Jr, Roth BL, Peterson RT, Shoichet BK. Nat Chem Biol 2011 **Co-first author
- Rapid behavior-based identification of neuroactive small molecules in the zebrafish. Kokel D, Bryan J, Laggner C, White R, Cheung CY, Mateus R, Healey D, Kim S, Werdich AA, Haggarty SJ, Macrae CA, Shoichet B, Peterson RT. Nat Chem Biol. 2010
- Zebrafish behavioral profiling links drugs to biological targets and rest/wake regulation. Rihel J, Prober DA, Arvanites A, Lam K, Zimmerman S, Jang S, Haggarty SJ, Kokel D, Rubin LL, Peterson RT, Schier AF. Science 2010
- Chemobehavioural phenomics and behaviour-based psychiatric drug discovery in the zebrafish. Kokel D, Peterson RT. Brief Funct Genomic Proteomic. 2008